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These Isotoner Therapeutic Compression Gloves are comfortable, economical gloves provide gentle compression to help control edema. All are washable and sold individually. Latex free. To determine size, measure the circumference of the hand through the thumb web space. Extra Small is 7" or 17.8 cm., Small is 8" or 20.3 cm., Medium is 9" or 221.9 cm., Large is 10" or 25.4 cm.